Living With Optune Gio

Merging Optune Gio with patients’ lifestyles

Quick tips on living with Optune Gio

Most Optune Gio discontinuations happen within the first 90 days. Help your patients cross the 90-day threshold with the following tips on how they can incorporate Optune Gio into their everyday activities.

Array placement1

 

  • Patients should change arrays at least 2 times per week (every 4 days at most)
  • Patients should apply mineral oil to the scalp to gently peel off arrays and not pull the skin or forcefully rub the scalp to remove adhesive
  • To limit skin irritation, slightly shift the placement of the transducer arrays by about 0.75 inches from the last location during routine changes ensuring that pairs of arrays are moved together

Covering up

 

  • Patients can wear a baseball cap, sun hat, hood, or wig1
  • Hats and wigs should completely cover the arrays, while leaving space for ventilation2

Sleeping with Optune Gio

 

  • Bedside fans and cooling pillows have worked for many patients
  • Using the long cord provided with the device or hanging it close to their bedside while sleeping may allow for fewer interruptions during the night1

Encouraging a flexible schedule

 

  • While the recommended time for using Optune Gio is 18 hours a day, patients may bank hours—wearing the device more on some days and less on others—as long as they average ≥75% of a month using the device1

Banking hours looks different for everyone

See how patients make Optune Gio work for them

  • Miriam planned for a business trip by increasing her average daily use of Optune Gio before and after the trip when she was home
  • Kelvin wore Optune Gio for roughly the same number of hours each day

Examples are hypothetical and do not represent real patients.

Note: Patients should contact their Device Support Specialist if they plan to travel and if they have questions related to travel restrictions.

The Buddy Program

  • The Optune Gio Buddy Program connects your patients with other users that can help them navigate daily life with Optune Gio
  • Buddies give one-on-one support and share helpful learnings from using Optune Gio
Connect patients with a buddy

References: 1. Optune Gio. Patient Information and Operation Manual. Novocure; 2023. 2. Lacouture ME, Anadkat MJ, Ballo MT, et al. Prevention and management of dermatologic adverse events associated with Tumor Treating Fields in patients with glioblastoma. Front Oncol. 2020;10:1045. doi:10.3389/fonc.2020.01045

Indications For Use

Optune Gio® is intended as a treatment for adult patients (22 years of age or older) with histologically confirmed glioblastoma multiforme (GBM).

 

Optune Gio with temozolomide is indicated for the treatment of adult patients with newly diagnosed, supratentorial glioblastoma following maximal debulking surgery, and completion of radiation therapy together with concomitant standard of care chemotherapy.

 

For the treatment of recurrent GBM, Optune Gio is indicated following histologically or radiologically confirmed recurrence in the supratentorial region of the brain after receiving chemotherapy. The device is intended to be used as a monotherapy and is intended as an alternative to standard medical therapy for GBM after surgical and radiation options have been exhausted.
 

Important Safety Information

Contraindications

Do not use Optune Gio in patients with an active implanted medical device, a skull defect (such as, missing bone with no replacement), or bullet fragments. Use of Optune Gio together with implanted electronic devices has not been tested and may theoretically lead to malfunctioning of the implanted device. Use of Optune Gio together with skull defects or bullet fragments has not been tested and may possibly lead to tissue damage or render Optune Gio ineffective.

 

Do not use Optune Gio in patients that are known to be sensitive to conductive hydrogels. In this case, skin contact with the gel used with Optune Gio may commonly cause increased redness and itching, and rarely may even lead to severe allergic reactions such as shock and respiratory failure.

 

Warnings and precautions

Optune Gio can only be prescribed by a healthcare provider that has completed the required certification training provided by Novocure (the device manufacturer).

 

Do not prescribe Optune Gio for patients that are pregnant, you think might be pregnant or are trying to get pregnant, as the safety and effectiveness of Optune Gio in these populations have not been established.

 

The most common (≥10%) adverse events involving Optune Gio in combination with temozolomide were thrombocytopenia, nausea, constipation, vomiting, fatigue, medical device site reaction, headache, convulsions, and depression.

 

The most common (≥10%) adverse events seen with Optune Gio monotherapy were medical device site reaction and headache.
The following adverse reactions were considered related to Optune Gio when used as monotherapy: medical device site reaction, headache, malaise, muscle twitching, fall, and skin ulcer.

 

Use of Optune Gio in patients with an inactive implanted medical device in the brain has not been studied for safety and effectiveness, and use of Optune Gio in these patients could lead to tissue damage or lower the chance of Optune Gio being effective.

 

If the patient has an underlying serious skin condition on the scalp, evaluate whether this may prevent or temporarily interfere with Optune Gio treatment.

Please click here to see the Optune Gio® Instructions For Use for complete information regarding the device’s indications, contraindications, warnings, and precautions.

Novocure Websites

This website is intended for people seeking information on Optune Gio.

 

On this site, videos and images identified as Optune Gio users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals.

 

Patient images reflect the health status of the patients at the time each photo or video was taken.

 

External links

Optunegio.com
Optunelua.com
Novocuretrials.com

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US-OPG-00197v1.0 February 2025 

 

US-OPG-00197 v1.0 February 2025